Modulation by EEG features of BOLD responses to interictal epileptiform discharges
نویسندگان
چکیده
منابع مشابه
Modulation by EEG features of BOLD responses to interictal epileptiform discharges
INTRODUCTION EEG-fMRI of interictal epileptiform discharges (IEDs) usually assumes a fixed hemodynamic response function (HRF). This study investigates HRF variability with respect to IED amplitude fluctuations using independent component analysis (ICA), with the goal of improving the specificity of EEG-fMRI analyses. METHODS We selected EEG-fMRI data from 10 focal epilepsy patients with a go...
متن کاملThe BOLD response to interictal epileptiform discharges.
We studied single-event and average BOLD responses to EEG interictal epileptic discharges (IEDs) in four patients with focal epilepsy, using continuous EEG-fMRI during 80-min sessions. The detection of activated areas was performed by comparing the BOLD signal at each voxel to a model of the expected signal. Since little is known about the BOLD response to IEDs, we modeled it with the response ...
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The diagnosis of epilepsy heavily depends on the detection of epileptiform discharges in interictal EEG, the EEG in between two seizures. By visual analysis a physician wants to detect these epileptiform discharges (spikes). Due to the wide variety of morphologies of epileptiform discharges, and their similarity to waves that are part of normal EEG or to artifacts, this detection is far from st...
متن کاملInterictal Epileptiform Discharges
EEG remains the primary technique in the diagnosis, characterization, and localization of partial seizures. This review examines the significance and character of interictal epileptiform abnormailites, periodic lateralized epileptiform discharges, and ictal patterns in patients with partial epilepsy. Interictal epileptiform discharges are common and assist in the diagnosis and localization of p...
متن کاملReproducible localization of interictal epileptiform discharges using EEG-triggered fMRI.
We report preliminary experiences using fMRI triggered by EEG to localize the site of interictal epileptiform activity. EEG was recorded in the scanner and monitored on-line; the recording quality was good enough to allow the clear identification of spikes in the EEG. Snap-shot EPI was performed 2-4 s after an epileptiform discharge ('spike') or after at least 10 s of background activity ('rest...
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ژورنال
عنوان ژورنال: NeuroImage
سال: 2010
ISSN: 1053-8119
DOI: 10.1016/j.neuroimage.2009.12.044